Ibuprofen

Aliases: Motrin, Advil 

Indications: Pain, fever, swelling from an acute injury 

Contraindications: Known hypersensitivity. Should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Known pregnancy. Should be avoided in patient with advanced kidney disease.    

Concentrations: 

Solution: 20mg/mL

Dosing

Adult:

Indication	Dose	Route	Note
-Analgesia (any level) -Fever -Swelling from acute injury	600 mg	PO	-One dose only.  -May combine with acetaminophen.  -Avoid in headache

Pediatric:

Indication	Dose	Route	Note
-Analgesia (any level) -Fever -Swelling from acute injury	10 mg/kg Max: 600 mg	PO	-Must be over 6 months old -One dose only.  -May combine with acetaminophen.  -Avoid in headache

Precautions: None

Adverse/Side Effects: Aspirin-sensitive asthma, coagulation disorders or patients receiving anticoagulants should be carefully monitored.   

Class: Non-Steroidal Anti-Inflammatory Drug (NSAID)  

Mechanism of Action: Ibuprofen possesses analgesic and antipyretic activities. Its mode of action, like that of other NSAIDs, is not completely understood, but may be related to prostaglandin synthetized inhibition, by blocking the enzyme in your body that makes prostaglandins. Decreasing prostaglandins helps to reduce pain, swelling, and fever.

Onset of Action	Peak Effect	Duration of Action
30 to 60 minutes	1 to 2 hours	6 to 8 hours