Calcium Channel Blocker Overdose 

Assessment

Pediatric Pearls: Signs & Symptoms: Differential: 
□ Fluids and medications titrated to maintain SBP > 70 + (age x 2) mmHg □ Bradycardia
□ Hypotension
□ Decreased AV Nodal conduction
□ Cardiogenic shock
□ Hyperglycemia
seizures
□ Sepsis
□ Hypoxia
□ Hypoglycemia

Clinical Management Options

EMT-B
• Place in position of comfort
Oxygen target SpO2 92% – 96%  
• Obtain blood glucose level
Paramedic
• IV / IO access as appropriate for patient condition 
• Obtain an EKG
• Consider atropine sulfate for symptomatic bradycardia
• Adult: atropine 0.5 mg IV every 5 minutes to maximum of 3 mg
• Pediatric: atropine 0.02 mg/kg (0.1 to 0.5 mg per dose) every 5 minutes, maximum total dose 1 mg
• Consider calcium chloride
• Adult: Calcium chloride 1 g slow IVP
• Pediatric: Calcium chloride 20 mg/kg (0.2 mL/kg) slow IVP/IO. Maximum dose 1 g or 10 mL
• Consider IV fluid 20 mL/kg up to 1 liter, repeat as indicated
• Consider vasopressors after adequate fluid resuscitation for the hypotensive patient
• Consider Glucagon if atropine, calcium, and vasopressors have failed:
• Glucagon 1 mg IVP (Over 25 kg)
• Glucagon 0.5 mg IVP (less than 25 kg)
• Consider transcutaneous pacing if refractory to initial pharmacologic interventions
Consult Online Medical Control as Needed